Molecular Biology: Academic Cell 2/e
暫譯: 分子生物學：學術細胞 2/e
Clark
- 出版商: ELSEVIER HEALTH
- 出版日期: 2012-01-01
- 售價: $1,280
- 貴賓價: 9.8 折 $1,254
- 語言: 英文
- 頁數: 924
- 裝訂: 平裝
- ISBN: 9866052192
- ISBN-13: 9789866052194
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相關分類:
生物資訊 Bioinformatics
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相關主題
商品描述
Description
The last quarter of the 20th century saw major scientific revolutions in genetics and computer technology. This book reflects this massive surge in our understanding of the molecular foundations of genetics. In order to understand where these technological advances are heading, there needs to be a basic understanding of how living organisms function at a molecular level. Molecular Biology, 2e, effectively introduces basic concepts followed by more specific applications as the text evolves. With the addition of Cell Press articles, the content is tied to current topics in the scientific community.
Changes in the Second Edition
This edition includes significant changes in comparison to the first edition of Molecular Biology.
The flood of new sequence information has necessitated updates to many areas of the book, especially Genomics and Systems Biology (Ch. 9), Proteomics (Ch. 15) Bacterial Genetics (Ch. 25), and Molecular Evolution (Ch. 26). Perhaps the mostrapidly-changing area of molecular biology at present is the ever-expanding role of RNA. Although scattered items occur throughout the book, particularly in Unit 4, most of the major novel RNA topics, such as CRISPR and long-non-coding RNA, are grouped together in Chapter 18, Regulation at the RNA level.
In this second edition we have re-ordered some of the chapters in a more logical order. In particular， chapters on DNA technology and genomics that were toward the end of the book have been moved far forward. This reflects the much greater role that sequence analysis and genomics have come to play in the last two or three years.
We have also divided the book into modules， each of several related chapters. The first module contains introductory material that experienced students can either skip or skim through rapidly for the reasons cited above. Sections within chapters have been numbered to aid in cross-reference. Review questions and conceptual problems are now provided at the end of each chapter.
A new text element, "Focus on Relevant Research," now appears throughout the book. These feature discussions of recent papers in the field published by Cell Press. The content focuses on helping the student learn how to read and understand primary literature in hopes of preparing them for the scientific world. The complete articles are also provided on the accompanying website for easy reference by students and instructors.
The website also includes access to the Focus on Relevant Research Case Studies that discuss the main topics of each chapter and build case studies around the content to help students understand the basics of primary literature while allowing them to make the appropriate connections to the text.
商品描述(中文翻譯)
描述
20世紀最後一個季度見證了遺傳學和計算機技術的重大科學革命。本書反映了我們對遺傳學分子基礎理解的巨大增長。為了理解這些技術進步的方向，需要對生物體在分子層面上的運作有基本的了解。Molecular Biology, 2e，有效地介紹了基本概念，隨著文本的發展，隨後是更具體的應用。隨著Cell Press文章的加入，內容與科學社群中的當前主題相連結。
第二版的變更
本版與《Molecular Biology》第一版相比，包含了重大變更。
新的序列信息的洪流使得書中許多領域需要更新，特別是基因組學和系統生物學（第9章）、蛋白質組學（第15章）、細菌遺傳學（第25章）和分子進化（第26章）。目前分子生物學中變化最快的領域可能是RNA的日益擴展的角色。雖然書中各處都有零散的項目，特別是在第4單元，但大多數主要的新穎RNA主題，如CRISPR和長非編碼RNA，集中在第18章，RNA層面的調控。
在這第二版中，我們重新排列了一些章節，使其更具邏輯性。特別是，書末的DNA技術和基因組學章節已被提前移動，這反映了序列分析和基因組學在過去兩三年中所扮演的更大角色。
我們還將本書劃分為模塊，每個模塊包含幾個相關的章節。第一個模塊包含了經驗豐富的學生可以跳過或快速瀏覽的入門材料，原因如上所述。章節內的部分已編號，以便於交叉參考。每章末尾現在提供了回顧問題和概念性問題。
一個新的文本元素“聚焦相關研究”現在出現在全書中。這些部分討論了Cell Press發表的該領域最近的論文。內容重點在於幫助學生學會如何閱讀和理解原始文獻，以期為他們進入科學界做好準備。完整的文章也在隨附的網站上提供，方便學生和教師參考。
該網站還包括訪問“聚焦相關研究案例研究”，討論每章的主要主題，並圍繞內容構建案例研究，以幫助學生理解原始文獻的基本知識，同時使他們能夠與文本建立適當的聯繫。
作者簡介
David Clark, BA (honors)Christ's College Cambridge, 1973 PhD University of Brsitol (England), 1977, Southern Illinois University, Carbondale, Illinois, USA
Nanette Pazdernik, School of Medicine at Washington University, St. Louis, Missouri, USA
作者簡介(中文翻譯)
大衛·克拉克，劍橋大學基督學院榮譽學士，1973年，布里斯托大學（英國）博士，1977年，美國伊利諾伊州卡本代爾南伊利諾伊大學
南妮特·帕茲德尼克，美國密蘇里州聖路易斯華盛頓大學醫學院
目錄大綱
Unit 1: Basic Chemical and Biological Principles
Ch1 Cells and Organisms
Ch2 Basic Genetics
Ch3 DNA, RNA, and Protein
Ch4 Genomes and DNA
Ch5 Manipulation of Nucleic Acids
Unit 2: The Genome
Ch6 Polymerase Chain Reaction
Ch7 Cloning Genes for Analysis
Ch8 DNA Sequencing
Ch9 Genomics & Systems Biology
Unit 3: The Central Dogma of Molecular Biology
Ch10 Cell Division and DNA Replication
Ch11 Transcription of Genes
Ch12 Processing of RNA
Ch13 Protein Synthesis
Ch14 Protein Structure & Function
Ch15 Proteomics: The Global Analysis of Proteins
Unit 4: Regulating Gene Expression
Ch16 Regulation of Transcription in Prokaryotes
Ch17 Regulation of Transcription in Eukaryotes
Ch18 Regulation at RNA Level
Ch19 Analysis of Gene Expression
Unit 5: Subcellular Life Forms
Ch20 Plasmids
Ch21 Viruses
Ch22 Mobile DNA
Unit 6: Changing the DNA Blueprint
Ch23 Mutations and Repair
Ch24 Recombination
Ch25 Bacterial Genetics
Ch26 Molecular Evolution
目錄大綱(中文翻譯)
Unit 1: Basic Chemical and Biological Principles
Ch1 Cells and Organisms
Ch2 Basic Genetics
Ch3 DNA, RNA, and Protein
Ch4 Genomes and DNA
Ch5 Manipulation of Nucleic Acids
Unit 2: The Genome
Ch6 Polymerase Chain Reaction
Ch7 Cloning Genes for Analysis
Ch8 DNA Sequencing
Ch9 Genomics & Systems Biology
Unit 3: The Central Dogma of Molecular Biology
Ch10 Cell Division and DNA Replication
Ch11 Transcription of Genes
Ch12 Processing of RNA
Ch13 Protein Synthesis
Ch14 Protein Structure & Function
Ch15 Proteomics: The Global Analysis of Proteins
Unit 4: Regulating Gene Expression
Ch16 Regulation of Transcription in Prokaryotes
Ch17 Regulation of Transcription in Eukaryotes
Ch18 Regulation at RNA Level
Ch19 Analysis of Gene Expression
Unit 5: Subcellular Life Forms
Ch20 Plasmids
Ch21 Viruses
Ch22 Mobile DNA
Unit 6: Changing the DNA Blueprint
Ch23 Mutations and Repair
Ch24 Recombination
Ch25 Bacterial Genetics
Ch26 Molecular Evolution
