New Biology for Engineers and Computer Scientists

Aydin Tozeren, Stephen W. Byers

  • 出版商: Prentice Hall
  • 出版日期: 2003-05-09
  • 售價: $808
  • 語言: 英文
  • 頁數: 304
  • 裝訂: Paperback
  • ISBN: 0130664634
  • ISBN-13: 9780130664631
  • 下單後立即進貨 (約5~7天)

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商品描述

 

For biology courses in engineering and computer science departments.

Taking a system approach to expose modern biology, this book presents the fundamental system principles and parameters common to all living species. The straightforward examination begins with a presentation of molecular cell biology and progresses to the complex interrelationship between genes and proteins as observed in metabolic process, signal transduction, cell division and embryonic development. The text's unique approach provides a depiction of the human genome project, a review of high throughput biology and bioinformatic tools and a presentation of gene circuitry and pathway analysis as applied to cell division, development of embryo and metabolic pathways and expose of emerging proteomic science.

Table of Contents:

1. The Chemistry of Life.

Atoms. Molecules and Covalent Bonds. Ionic Compounds and Electrostatic Bonds. Water and Hydrogen Bonds. Lipids and Van der Waals Attratction. Acids and Bases. Chemical Reactions. Enzymes. More on Bioelements.

2. Macromolecules of Life.

Fundamentals. Carbohydrates. Lipids. DNA & RNA. Proteins. Genetic Code. Protein Structure and Function.

3. Cells and Their Housekeeping Functions.

Prokaryotes and Eukaryotes. Nuceleus. Organelles for Protein Synthesis and Transport. Cytoskeleton. Metabolic Processes and Mitochondria. Molecular Motors. Cell Membrane. Active Membrane Transport.

4. Gene Circuits.

Gene to Protein. Gene Anatomy. Gene Circuits. Bionetworks.

5. Genomics.

History of the Genome. Sequence Similarity and Homologous Genes. Decoding the Human Genome. Cutting and Sizing DNA. Making Multiple Copies. Sequencing. Gene Annotation. Plants and Animals with Modified Genomes.

6. Cell Adhesion and Communication.

Modes of Cell Communication. Extracellular Matrix and Integrins. Cell-cell Adhesions and Cadherine. Examples from Signal Transduction Pathways. Crosstalk between Signal Transduction Pathways.

7. Cell Division and its Regulation.

Modes of Cell Division. Molecular Basis of Cell Division. Cell Cycle Check Points. Phases of the Cell Cycle. Cell Culture.

8. Development of Multicellular Organisms.

From Unfertilized Egg to Zygote. Cleavage: First Stage of Development. Gastrulation. Pattern-Generating Genes. Stem Cells and Tissue Engineering.

9. Large Scale Biology.

Microarrays. Proteomics. Protein Structure. System Biology.

Glossary.

商品描述(中文翻譯)

對於工程和電腦科學系的生物學課程,本書採用系統方法來介紹現代生物學,呈現了所有生物物種共有的基本系統原則和參數。這本書從分子細胞生物學開始,進一步探討基因和蛋白質在代謝過程、信號傳遞、細胞分裂和胚胎發育中的複雜相互關係。本書獨特的方法還介紹了人類基因組計劃,高通量生物學和生物信息學工具的概述,以及應用於細胞分裂、胚胎發育和代謝途徑的基因電路和通路分析,以及新興蛋白質組學科學的揭示。

目錄:
1. 生命的化學。
2. 生命的大分子。
3. 細胞及其基本功能。
4. 基因電路。
5. 基因組學。
6. 細胞黏附和通訊。
7. 細胞分裂及其調控。
8. 多細胞生物的發育。
9. 大規模生物學。

附錄:詞彙表。