Biomedical Applications and Toxicity of Nanomaterials

Mohanan, P. V., Kappalli, Sudha

Biomedical Applications and Toxicity of Nanomaterials
  • 出版商: Springer
  • 出版日期: 2024-05-10
  • 售價: $7,700
  • 貴賓價: 9.5 折 $7,315
  • 語言: 英文
  • 頁數: 768
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 9811978360
  • ISBN-13: 9789811978364

    • 海外代購書籍(需單獨結帳)

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商品描述

This book covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of informationfor industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.

商品描述(中文翻譯)

本書涵蓋了生物應用納米材料的最新趨勢，以及其製備方法和表徵技術。此外，本書還探討了納米毒性的基礎知識，評估工程納米材料毒性的方法，以及在合成過程中減少毒性的方法。它還概述了基於人工智能的方法在評估藥物和納米粒子毒性方面的最新進展。本書進一步討論了納米載體設計、各種納米粒子給藥途徑、基於納米技術的藥物傳遞系統，以及與每種藥物傳遞方法相關的毒性挑戰。它介紹了納米粒子與細胞環境的相互作用的最新進展，並評估了這些工程納米粒子的毒性。本書還探討了納米材料的比較和機制性基因毒性評估。本書對於工業從業人員、政策制定者以及毒理學、醫學、藥理學、食品和藥物等領域的其他專業人士來說是一個有用的信息來源。

作者簡介

Dr. Mohanan is a Fellow of the National Academy of Science and Royal Society of Biologists, UK. He was a JSPS Postdoctoral Fellow at the University of Tsukuba, Japan in the field of Neurotoxicity. He joined Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Govt. of India in 1989. As a toxicologist, he has been intimately associated with all the medical devices/technologies developed at SCTIMST. Currently, he heads the Division of Toxicology. He is a Visiting Professor and Visiting Researcher at Toyo University, Japan, and a Certified Biological Safety Specialist. He received a lifetime achievement award from the Society of Toxicology India, for his outstanding contribution to the field of toxicology. Dr. Mohanan has been teaching toxicology to postgraduates and guiding research scholars. The development of Human-on-a-chip is a new mega project, apart from several other externally funded research projects. He has patented an ELISA kit for the measurement of pyrogenicity and has made significant contributions to the development of medical device regulations in India. He received a certificate of appreciation from the Hon. Minister of Science and Technology, Govt. of India for the contribution to India getting full adherent status on GLP from OECD. He has authored 262 publications and edited 5 books. Presently, He is the Secretary-General of Society of Toxicology, India.

Dr. Sudha Kappalli is a Professor in the Department of Zoology, School of Biological Science, Central University of Kerala. Her research Areas include, Crustacean Growth - Reproduction interaction and its endocrine regulation, biodiversity of parasitic isopods and copepods and host-parasite interaction. She has obtained PhD from University of Calicut in 1993. She has 27 years of teaching experience at P.G level. Recipient of CAS-PIFI Visiting Scientist Fellowship (2015), CAS-TWAS Visiting Scholar Fellowship (2009 and 2011), Commonwealth Academic Staff Fellowship (2007), INSA Visiting Scientist Fellowship (2007) and IAS Summer Teacher Fellowship (2005) and University Post-Doctoral Fellowship (1994). She has completed four major research projects funded by International Foundation for Science (Stockholm, Sweden), BRNS, UGC, KSCSTE and SERB as Principal Investigator. She has currently PI of three research projects funded by KSCSTE, DST-RFBR and DST-JSPS and published 40 research papers in the peer reviewed journals and 6 papers in conference proceedings with one book chapter. Dr. Sudha serves as a member for several professional and academic bodies of universities and government agencies. In honour of excellence in teaching. Dr. Sudha was chosen for Dr. P.K. Rajan Memorial Excellent Award (2012), Prof. Sivaprasad Memorial Award (2013) and St. Berchmans Award (2013) for Best College Teacher in Kerala.

作者簡介(中文翻譯)

Dr. Mohanan是英國國家科學院和英國皇家生物學家學會的院士。他曾在日本筑波大學擔任JSPS博士後研究員，研究領域是神經毒性。他於1989年加入印度政府的Sree Chitra Tirunal醫學科學與技術研究所（SCTIMST）。作為一名毒理學家，他與SCTIMST開發的所有醫療設備/技術密切相關。目前，他負責毒理學部門。他是日本東洋大學的客座教授和客座研究員，也是一名經過認證的生物安全專家。他因對毒理學領域的傑出貢獻而獲得了印度毒理學學會頒發的終身成就獎。Mohanan博士一直在教授毒理學給研究生並指導研究學者。除了其他外部資助的研究項目外，人體晶片的開發是一個新的大型項目。他已經申請了一項用於測量熱原性的ELISA試劑盒的專利，並對印度醫療設備監管的發展做出了重要貢獻。他因對印度獲得OECD GLP全面遵從地位的貢獻而獲得了印度科技部部長的感謝狀。他撰寫了262篇論文並編輯了5本書。目前，他是印度毒理學學會的秘書長。

Dr. Sudha Kappalli是中央喀拉拉邦大學生物科學學院動物學系的教授。她的研究領域包括甲殼類生長-繁殖相互作用及其內分泌調節、寄生性等足動物和橈足動物的生物多樣性以及宿主-寄生物相互作用。她於1993年在卡利卡特大學獲得博士學位。她在研究生教學方面擁有27年的教學經驗。她曾獲得CAS-PIFI訪問科學家獎學金（2015年）、CAS-TWAS訪問學者獎學金（2009年和2011年）、英聯邦學術人員獎學金（2007年）、INSA訪問科學家獎學金（2007年）和IAS暑期教師獎學金（2005年）以及大學博士後獎學金（1994年）。她作為主要研究者完成了由國際科學基金會（瑞典斯德哥爾摩）、BRNS、UGC、KSCSTE和SERB資助的四個重大研究項目。她目前是由KSCSTE、DST-RFBR和DST-JSPS資助的三個研究項目的主要研究者，並在同行評審期刊上發表了40篇研究論文和6篇會議論文，還有一章書籍章節。Sudha博士是多所大學和政府機構的專業和學術機構的成員。為表彰其卓越的教學成就，Sudha博士獲得了P.K. Rajan博士紀念優秀獎（2012年）、Sivaprasad教授紀念獎（2013年）和St. Berchmans獎（2013年），以表彰其在喀拉拉邦的最佳大學教師。

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