Hydrogel for Biomedical Applications: 3d/4D Printing, Self-Healing, Microrobots, and Nanogenerators

本書突顯了最新的臨床研究和3D（生物）打印以及使用刺激響應性水凝膠的4D打印的進展，以及自癒概念及其與3D打印的可注射細胞載體組織構建的融合。它還探討了無金屬“點擊”化學和酶（如辣根過氧化物酶、血紅素、酪氨酸酶和轉谷氨酰胺酶）在獲得化學交聯水凝膠以及體外和體內反應方面的應用。最後，本書簡要探討了藥物傳遞的未來以及基於摩擦電納發電機的微機器人和自供電設備所提供的潛力。本書適合從事組織重建和藥物/治療傳遞的生物醫學研究人員和臨床醫生閱讀。

Dr. Andy H. Choi is an early career researcher who received his Ph.D. from the University of Technology Sydney (UTS) in Australia in 2004 on the use of computer modeling and simulation known as finite element analysis (FEA) to examine the biomechanical behavior of implants installed into a human mandible. After completing his Ph.D., he expanded his research focus from FEA to sol-gel synthesis of multifunctional calcium phosphate nanocoatings and nanocomposite coatings for dental and biomedical applications. In late 2010, Dr. Choi was successfully awarded the internationally competitive Endeavour Australia Cheung Kong Research Fellowship Award and undertook post-doctoral training at the Faculty of Dentistry of the University of Hong Kong focusing on the application of FEA in dentistry and the development of calcium phosphate nano-bioceramics. He is currently serving as an associate editor for the Journal of the Australian Ceramic Society and as an editor for a number of dentistry-related journals. In addition, he is also serving as an editorial board member for several dentistry, nanotechnology, and orthopedics journals. To date, Dr. Choi has published over 50 publications including 8 books and 30 book chapters on calcium phosphate, nano-biomaterial coatings, sol-gel technology, marine structures, drug delivery, tissue engineering, and finite element analysis in nanomedicine and dentistry.

Besim Ben-Nissan Professor Ben-Nissan has higher degrees in Metallurgical Engineering (ITU), Ceramic Engineering (University of New South Wales), and a Ph.D. in Mechanical and Industrial Engineering with Biomedical Engineering (University of New South Wales). Over the last four decades together with a large numbers of Ph.D. students and post-doctoral fellows, he has worked on production and analysis of various biomedical materials, implants, calcium phosphate ceramics, advanced ceramics (alumina, zirconia, silicon nitrides), sol-gel developednanocoatings for enhanced bioactivity, corrosion and abrasion protections, optical and electronic ceramics, and thermally insulating new generation composites. He also has contributed to the areas of mechanical properties of sol-gel developed nanocoatings. In the biomedical field, he has involved with the development of materials for slow drug delivery, natural and marine material conversion, implant technology (bioactive materials including conversion of Australian corals to hydroxyapatite bone grafts), biomimetics (learning from nature and its application to regenerative medicine), bio-composites, investigative research on biomechanics and finite element analysis (mandible, knee, hip joints, hip resurfacing), reliability, and implant design (modular ceramic knee prosthesis, femoral head stresses). He was part of a research team which initiated the world's first reliable ceramic knee and hydroxyapatite sol-gel-derived nanocoatings. Since 1990 he has published over 260 papers in journals, five books, and over 50 book chapters. He is one of the editors of the Journal of the Australian Ceramic Society and the editorial board member of three international biomaterials journals. He was awarded "The Australasian Ceramic Society Award" for his contribution to "Ceramic education and research and development in Australia." He also received "Future Materials Award" for his contribution to the "Advanced nanocoated materials field." He has collaborated with a number of international groups in Japan, USA, Thailand, Finland, Israel, France, UK, Germany, and Turkey and held grants from the Australian Academy of Science and the Japan Society for Promotion of Science for collaborative work in the biomedical field in Europe, USA, and Japan respectively. After serving as an academic for over 33 years, he has retired, however still active, and contributes to science by research in the biomedical field and supervising higher degree students.

Dr. Andy H. Choi是一位早期職業研究員，於2004年在澳洲悉尼科技大學（UTS）獲得博士學位，研究領域為使用有限元分析（FEA）的計算機建模和模擬，以檢驗植入人顎骨的植入物的生物力學行為。在完成博士學位後，他將研究重點從FEA擴展到多功能鈣磷酸鹽納米塗層和納米複合塗層的溶膠凝膠合成，用於牙科和生物醫學應用。2010年底，Choi博士成功獲得國際競爭力的Endeavour Australia Cheung Kong研究獎學金，並在香港大學牙科學院進行博士後培訓，專注於FEA在牙科學中的應用和鈣磷酸鹽納米生物陶瓷的開發。他目前擔任《澳大利亞陶瓷學會期刊》的副編輯，並擔任多個與牙科相關的期刊的編輯。此外，他還擔任幾個牙科、納米技術和骨科期刊的編輯委員會成員。迄今為止，Choi博士已發表了50多篇論文，包括8本書和30篇書籍章節，涉及鈣磷酸鹽、納米生物材料塗層、溶膠凝膠技術、海洋結構、藥物傳遞、組織工程和納米醫學和牙科中的有限元分析等領域。

Besim Ben-Nissan教授在冶金工程（ITU）、陶瓷工程（新南威爾士大學）和機械與工業工程（新南威爾士大學）方面擁有高等學位，並擁有機械與工業工程（生物醫學工程）的博士學位。在過去的四十年中，他與眾多博士生和博士後研究員一起，從事各種生物醫學材料、植入物、鈣磷酸鹽陶瓷、先進陶瓷（氧化鋁、氧化鋯、氮化矽）、溶膠凝膠開發的納米塗層（用於增強生物活性、防腐蝕和防磨損）、光學和電子陶瓷以及保溫新一代複合材料的生產和分析。他還為溶膠凝膠開發的納米塗層的機械性能做出了貢獻。在生物醫學領域，他參與了慢速藥物傳遞材料的開發、天然和海洋材料轉化、植入物技術（包括將澳大利亞珊瑚轉化為羥基磷灰石骨移植物）、仿生學（從自然中學習並應用於再生醫學）、生物複合材料、生物力學和有限元分析（顎骨、膝蓋、髖關節、髖關節表面置換）、可靠性和植入物設計（模塊化陶瓷膝關節假體、股骨頭應力）。他曾是一個研究團隊的一員，該團隊啟動了世界上第一個可靠的陶瓷膝關節和羥基磷灰石溶膠凝膠衍生的納米塗層。自1990年以來，他在期刊上發表了260多篇論文，出版了五本書和50多篇書籍章節。他是《澳大利亞陶瓷學會期刊》的編輯之一，也是三個國際生物材料期刊的編輯委員會成員。他因對澳大利亞的陶瓷教育和研發做出的貢獻而獲得了“澳大利亞陶瓷學會獎”，並因對“先進納米塗層材料領域”的貢獻而獲得了“未來材料獎”。他與日本、美國、泰國、芬蘭、以色列、法國、英國、德國和土耳其的多個國際團隊合作，並獲得澳大利亞科學院和日本學術振興會的資助，分別在歐洲、美國和日本的生物醫學領域進行合作研究。在擔任學術人員超過33年後，他已經退休，但仍然活躍，通過在生物醫學領域進行研究和指導高等學位學生來貢獻於科學。