Omics Approaches in Biomedicine and Biotechnology: From Technologies to Data to Biological Knowledge
暫譯: 生物醫學與生物技術中的組學方法：從技術到數據再到生物知識

Gama-Carvalho, Margarida, Figueiredo, Andreia, Pinto, Francisco Rodrigues

Omics Approaches in Biomedicine and Biotechnology: From Technologies to Data to Biological Knowledge
  • 出版商: Springer
  • 出版日期: 2026-05-05
  • 售價: $10,100
  • 貴賓價: 9.5 折 $9,595
  • 語言: 英文
  • 頁數: 459
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 3032189659
  • ISBN-13: 9783032189653
  • 相關分類: 生物資訊 Bioinformatics

    • 海外代購書籍(需單獨結帳)

相關主題

商品描述

This book explores current omics technologies and provides researchers with a comprehensive understanding of them.

In recent years, technological advances have transformed the life sciences, ushering in the era of "omics" approaches. These methods, which emerged in the wake of the Human Genome Project, are driven by the need to systematically understand genomic diversity and gene expression. They have ushered in the age of big data in the life sciences, revolutionising the way biological questions are asked and experimental results are handled.

Omics approaches cover a wide range of applications, from mapping environmental biodiversity to characterising molecular interactions and small molecules. Despite the current accessibility of these technologies, most researchers and students in the life sciences have had limited exposure to the field, preventing them from fully grasping the power and limitations of the technology, or the critical importance of tailored experimental design and data analysis.

The challenges that are posed by omics technologies are addressed in this book. It provides a comprehensive overview and shows how omics approaches can be effectively used to gain innovative insights into specific biological problems.

The book is divided into three main parts: -

  • Part I Capturing the Molecular Universe, provides an in-depth exploration of the current technologies, highlighting their potential and limitations.
  • Part II From Large Scale Data to Biological Insights, offers a practical introduction to the world of data generated by omics methodologies, emphasizing data sharing, management, and analysis, with a focus on readers in the biological sciences.
  • Part III Application of Omics Approaches, outlines various applications of omics technologies in biomedicine and biotechnology, offering insights into their current use and future potential.

The book is a valuable resource for both seasoned researchers and those entering the field, facilitating a deeper understanding of omics approaches and their transformative impact on the life sciences.

With illustrations by Filipa Santos.

商品描述(中文翻譯)

本書探討當前的組學技術，並為研究人員提供全面的理解。

近年來，技術進步改變了生命科學，開創了「組學」方法的時代。這些方法是在人體基因組計畫之後出現的，旨在系統性地理解基因組多樣性和基因表達。它們引領了生命科學中的大數據時代，徹底改變了生物學問題的提出方式和實驗結果的處理方式。

組學方法涵蓋了廣泛的應用，從環境生物多樣性的繪製到分子互動和小分子的特徵描述。儘管這些技術目前已經相對可及，但大多數生命科學的研究人員和學生對該領域的接觸仍然有限，這使他們無法充分理解這項技術的優勢和局限性，以及量身定制的實驗設計和數據分析的重要性。

本書針對組學技術所帶來的挑戰進行了探討。它提供了全面的概述，並展示了如何有效地使用組學方法來獲得對特定生物問題的創新見解。

本書分為三個主要部分：
- 第一部分《捕捉分子宇宙》深入探討當前技術，突顯其潛力和局限性。
- 第二部分《從大規模數據到生物見解》提供了組學方法生成的數據世界的實用介紹，強調數據共享、管理和分析，特別針對生物科學領域的讀者。
- 第三部分《組學方法的應用》概述了組學技術在生物醫學和生物技術中的各種應用，提供了對其當前使用情況和未來潛力的見解。

本書是資深研究人員和新進入該領域者的寶貴資源，促進對組學方法及其對生命科學變革性影響的深入理解。

插圖由 Filipa Santos 提供。

作者簡介

Margarida Gama-Carvalho is an Associate Professor in the Department of Chemistry and Biochemistry at the Faculty of Sciences, University of Lisbon. She holds a PhD in Biomedical Sciences and is a Principal Investigator at BioISI, where she leads the RNA Systems Biology laboratory. She currently coordinates GenomePT, the Portuguese national research infrastructure for genome sequencing and analysis. Her research focuses on RNA-dependent regulation of gene expression in health and disease, integrating next-generation sequencing and multi-omics approaches to support the development of RNA-based therapeutic strategies.

Andreia Figueiredo is an Associate Professor in the Department of Biology at the Faculty of Sciences, University of Lisbon, and head of the BioISI Grapevine Pathogen Systems (GPS) Lab. She holds a PhD in Cellular and Molecular Biology. Her research addresses plant-pathogen interactions in grapevine using systems biology approaches that integrate multi-omics, functional genomics, and biotechnology, with the aim of elucidating disease regulatory networks and improving crop resilience for sustainable agricultural production.

Francisco Rodrigues Pinto is an Assistant Professor in the Department of Chemistry and Biochemistry at the Faculty of Sciences, University of Lisbon and co-Principal Investigator of the RNA Systems Biology laboratory at BioISI. He holds a PhD in Biochemistry and has extensive international research experience. His work focuses on the computational analysis and mathematical modeling of complex biological systems, including gene expression and regulatory networks, host-pathogen interactions, and disease mechanisms, with applications in cancer, microbiology, neurodegeneration, and cystic fibrosis.

作者簡介(中文翻譯)

Margarida Gama-Carvalho 是里斯本大學科學學院化學與生物化學系的副教授。她擁有生物醫學科學的博士學位，並且是BioISI的主要研究員，負責RNA系統生物學實驗室。她目前協調GenomePT，這是葡萄牙的國家基因組測序與分析研究基礎設施。她的研究專注於RNA依賴的基因表達調控，涵蓋健康與疾病，並整合下一代測序和多組學方法，以支持基於RNA的治療策略的發展。

Andreia Figueiredo 是里斯本大學科學學院生物學系的副教授，並且是BioISI葡萄病原系統（GPS）實驗室的負責人。她擁有細胞與分子生物學的博士學位。她的研究針對葡萄藤中的植物-病原體相互作用，使用系統生物學方法，整合多組學、功能基因組學和生物技術，旨在闡明疾病調控網絡並提高作物的抗逆性，以實現可持續農業生產。

Francisco Rodrigues Pinto 是里斯本大學科學學院化學與生物化學系的助理教授，也是BioISI RNA系統生物學實驗室的共同主要研究員。他擁有生物化學的博士學位，並擁有豐富的國際研究經驗。他的工作專注於複雜生物系統的計算分析和數學建模，包括基因表達和調控網絡、宿主-病原體相互作用以及疾病機制，並應用於癌症、微生物學、神經退行性疾病和囊性纖維化等領域。

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