Molecular and Cell Biology of Pancreas Development, Function and Regeneration

Golson, Maria L.

Molecular and Cell Biology of Pancreas Development, Function and Regeneration
  • 出版商: Springer
  • 出版日期: 2024-09-17
  • 售價: $4,790
  • 貴賓價: 9.5 折 $4,551
  • 語言: 英文
  • 頁數: 188
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 3031622316
  • ISBN-13: 9783031622311

    • 海外代購書籍(需單獨結帳)

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商品描述

This book reviews recent advances in pancreatic endocrine and exocrine tissue development, function and regeneration. It provides a comprehensive overview on different aspects of beta-cell biology, including heterogeneity of function and gene expression and function, epigenetics, RNA and protein expression contributions to beta-cell specification and cell-fate maintenance. Furthermore, it covers recent progress in differentiating functional islets in vivo, environmental impacts on beta-cell development and function, and communications between various islet endocrine cells and how they contribute to the regulation of blood glucose homeostasis.

The book provides a comprehensive resource for understanding the various compartments of the pancreas and is aimed at pancreas, beta-cell biology, and diabetes researchers.

商品描述(中文翻譯)

本書回顧了胰臟內分泌和外分泌組織發育、功能和再生的最新進展。它全面概述了β細胞生物學的不同方面，包括功能和基因表達的異質性、表觀遺傳學、RNA和蛋白質表達對β細胞特異性和細胞命運維持的貢獻。此外，它還介紹了在體內分化功能性胰島、環境對β細胞發育和功能的影響，以及不同胰島內分泌細胞之間的通訊以及它們如何參與調節血糖平衡的過程。

本書為了幫助讀者深入了解胰臟的各個組成部分，針對胰臟、β細胞生物學和糖尿病研究人員提供了一個全面的資源。

作者簡介

Dr. Maria Golson graduated from Duke University with a B.S. in Biology in 2000. She focused on pancreas development in her studies as a graduate student in the Cell and Molecular Biology Program at the University of Pennsylvania and graduated with a Ph.D. in 2008. She furthered her expertise in the beta-cell biology field at the Vanderbilt University as a postdoctoral fellow studying with Maureen Gannon. Starting in 2015, she followed up with a stint as a Research Assistant Professor in the Genetics Department at the University of Pennsylvania, where she coordinated the Human Pancreas Analysis Program under Klaus Kaestner while also studying the regulation of beta-cell function by intrinsic and extrinsic factors. In 2020, Dr. Golson joined the faculty in the Division of Endocrinology, Diabetes, and Metabolism at the Johns Hopkins University as an Asisstant Professor.

作者簡介(中文翻譯)

Dr. Maria Golson於2000年畢業於杜克大學，獲得生物學學士學位。她在賓夕法尼亞大學的細胞與分子生物學研究計劃中攻讀研究生時，專注於胰臟發育，並於2008年獲得博士學位。她在范德堡大學進一步深化了她在β細胞生物學領域的專業知識，作為一名博士後研究員在Maureen Gannon的指導下進行研究。從2015年開始，她在賓夕法尼亞大學的遺傳學系擔任研究助理教授，同時在Klaus Kaestner的指導下協調人類胰臟分析計劃，並研究內在和外在因素對β細胞功能的調節。2020年，Golson博士作為助理教授加入約翰霍普金斯大學內分泌學、糖尿病和新陳代謝學部。

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