Handbook of the Extracellular Matrix: Biologically-Derived Materials

Maia, F. Raquel, Oliveira, J. Miguel, Reis, Rui L.

  • 出版商: Springer
  • 出版日期: 2024-07-17
  • 售價: $26,720
  • 貴賓價: 9.5$25,384
  • 語言: 英文
  • 頁數: 1256
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 303156362X
  • ISBN-13: 9783031563621
  • 海外代購書籍(需單獨結帳)

商品描述

This book comprises 6 sections covering the fundamentals of the extracellular matrix, as well as the development and challenges of using biologically-derived materials, and its advanced biomedical applications. The first section is dedicated to the extracellular matrix, while the other 5 sections are each dedicated to a particular type of material. This book reports the fundamentals of the extracellular matrix and its impact on the development of innovative materials; provides an overview of the advanced methodologies used to develop biologically-derived materials; and describes the challenges of the synthesis and processing of the different materials. Furthermore, it presents the biological activities, structural and physicochemical properties of such materials, and the modification methods pursued to improve their inherent properties. The wide range of advanced applications are covered as well, including the combination with emerging technologies, underlying tissue-engineered scaffolding, drug delivery systems, 3D in vitro tissue and cancer models, 3D bioprinted models, bioinks, and more.

This reference work serves as a core reference for multidisciplinary students (undergraduates and Ph.D. students) and a wide range of established researchers and professionals working in the medical field, e.g., orthopaedics, radiology, dentistry, and cancer.

商品描述(中文翻譯)

本書分為6個部分,涵蓋了細胞外基質的基礎知識,以及使用生物衍生材料的發展和挑戰,以及其先進的生物醫學應用。第一部分專門介紹細胞外基質,而其他5個部分則分別專注於特定類型的材料。本書報導了細胞外基質的基礎知識及其對創新材料發展的影響;概述了開發生物衍生材料所使用的先進方法;描述了不同材料的合成和加工的挑戰。此外,本書還介紹了這些材料的生物活性、結構和物理化學性質,以及改善其固有性質的修飾方法。同時還涵蓋了廣泛的先進應用,包括與新興技術的結合,組織工程支架、藥物傳遞系統、3D體外組織和癌症模型、3D生物打印模型、生物墨水等。本參考書是跨學科學生(本科生和博士生)以及在醫學領域工作的各種專業研究人員和專業人士的核心參考資料,例如骨科、放射學、牙科和癌症等領域。

作者簡介

Dr. F. Raquel Maia obtained her Ph.D. in Biomedical Engineering from the University of Porto, in collaboration with the University of Nevada and University of Lisbon, in March 2014. In the same year, she started as a postdoctoral fellow at 3B's Research Group, University of Minho. In 2017, she was awarded an FCT postdoctoral fellowship, which gave place to a Junior Investigator contract. She is currently focused in the development of bioengineered materials to model 3D native microenvironments for Tissue Engineering and Regenerative Medicine and the development of physiologically relevant in vitro models-on-chip for cancer research.

Dr. J. Miguel Oliveira is a Biochemist and holds a PhD in Materials Science and Technology (2009). Currently, he is a Principal Investigator with habilitation (Permanent staff) and Vice-President of the Institute of Biomaterials, Biodegradables and Biomimetics (I3Bs), University of Minho (PT). He has been internationally recognized in the field of biomaterials, tissue engineering and in vitro models. In Nov. 2023, he was appointed Fellow Biomaterials Science and Engineering (FBSE) for the excellent professional standing and high achievements. He is also member of the National Ethics Committee for Clinical Research (CEIC) from the Portuguese National Health System (SNS, PT).

Prof. Rui L. Reis is a Full Professor, Founding Director of 3B´s Research Group and Dean of the Institute of Biomaterials, Biodegradables and Biomimetics (I3Bs), University of Minho (UMinho). He is Director and Scientific Coordinator of the Associate Laboratory ICVS/3B´s (with UMinho Medical School) since 2011 and the CEO of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine (TERM) since 2008. He is specially recognized for the introduction of several natural origin scaffolds and hydrogels with unique properties into the TERM field. He is one of the most well established, accomplished, and productive and highly-cited researchers in the World in the field of TERM and Biomaterials.

作者簡介(中文翻譯)

Dr. F. Raquel Maia於2014年3月在波爾圖大學獲得生物醫學工程博士學位,並與內華達大學和里斯本大學合作。同年,她開始在米尼奧大學的3B研究小組擔任博士後研究員。2017年,她獲得了FCT博士後獎學金,並轉為研究員合同。她目前致力於開發生物工程材料,用於模擬組織工程和再生醫學的3D原生微環境,以及開發與癌症研究相關的生理相關的體外模型。

Dr. J. Miguel Oliveira是一位生物化學家,並擁有材料科學和技術博士學位(2009年)。目前,他是米尼奧大學生物材料、生物可降解材料和仿生材料研究所(I3Bs)的主要研究員和副校長。他在生物材料、組織工程和體外模型領域享有國際聲譽。2023年11月,他因卓越的專業地位和高成就被任命為生物材料科學和工程(FBSE)研究員。他還是葡萄牙國家衛生系統(SNS)臨床研究國家倫理委員會(CEIC)的成員。

Rui L. Reis教授是3B研究小組的全職教授,也是米尼奧大學生物材料、生物可降解材料和仿生材料研究所(I3Bs)的創始主任和院長。自2011年以來,他一直擔任ICVS/3B聯合實驗室(與米尼奧大學醫學院合作)的主任和科學協調員,並自2008年起擔任組織工程和再生醫學卓越歐洲研究所(TERM)的首席執行官。他以引入幾種具有獨特性能的天然起源支架和水凝膠而受到特別認可。他是組織工程和生物材料領域中最有影響力、成就卓越、產出豐富且引用率極高的研究人員之一。