Reprogramming the Brain: A Guide to the Future of the Brain and Neuromodulation by a Patient and His Doctor
暫譯: 重新編程大腦：病人與醫生的未來大腦與神經調節指南
Stecher, Benjamin, Fasano, Alfonso
商品描述
In June 2021, Doctor and Patient decided that time had come to surgically implant two six-inch-long metal alloy spikes all the way through Ben's brain. It was felt that the medications Ben was taking to control his Parkinson's disease had become unmanageable.
Back then, Ben was taking about 20 different pills a day. Each pill, if it absorbed properly, would activate the dopamine pathways in his brain and induce uncontrollable writhing movements that would last for about an hour. He would then get about 20 minutes where he'd feel somewhat normal before the slowness and tremor kicked in again. So, he'd take another pill and the cycle would repeat.
After months of adjusting his medication and finding just the right settings on his deep brain stimulator, it was decided, for the first time ever in a clinical trial in North America, to flip on the adaptive settings.
This is the story of how that decision was made and what happened next.
商品描述(中文翻譯)
在2021年6月，醫生和病人決定是時候在本的腦中外科植入兩根六英寸長的金屬合金尖刺。因為本所服用的藥物已經無法有效控制他的帕金森病。
當時，本每天大約要服用20種不同的藥丸。每顆藥丸如果吸收得當，會激活他腦中的多巴胺通路，並引發無法控制的扭動，這種情況會持續約一小時。接著，他會有大約20分鐘的時間感覺稍微正常，然後緩慢和顫抖又會再次出現。因此，他會再服用另一顆藥丸，這個循環就會重複。
經過幾個月調整藥物和找到深腦刺激器的最佳設置後，決定在北美的臨床試驗中首次啟用自適應設置。
這是這個決定是如何做出的故事，以及接下來發生了什麼。
作者簡介
Benjamin Stecher is a patient advocate who chairs a number of advisory boards. He also recently had an adaptive deep brain stimulator implanted to better manage his symptoms of Parkinson's Disease. He is co-author of Brain Fables, which won the Prose Award in Neurosciences in 2020.
Alfonso Fasano, MD, PhD, FAAN is a movement disorder specialist at the University of Toronto's Movement Disorder Clinic and has over 25 years of experience with various neuromodulation techniques. He has published over 430 scientific manuscripts and written or edited 12 books and book chapters.
作者簡介(中文翻譯)
本傑明·斯特徹（Benjamin Stecher）是一位病患倡導者，擔任多個諮詢委員會的主席。他最近植入了一個自適應深腦刺激器，以更好地管理他的帕金森氏症症狀。他是《腦的寓言》（Brain Fables）的共同作者，該書於2020年獲得神經科學類的普羅斯獎（Prose Award）。
阿方索·法薩諾（Alfonso Fasano），醫學博士，哲學博士，FAAN，是多倫多大學運動障礙診所的運動障礙專家，擁有超過25年的各種神經調節技術的經驗。他已發表超過430篇科學論文，並撰寫或編輯了12本書籍和書章。
