Discovering Genomics, Proteomics, and Bioinformatics

A. Malcolm Campbell, Laurie J. Heyer

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Discovering Genomics, Proteomics, and Bioinformatics is the first textbook for upper-level undergraduates and first-year graduate students which combines integrated web exercises with a problem-solving approach to train students in basic hands-on genomic analysis. The authors present global problems, then provide the tools of genomic analysis to help students dissect the answer, thus encouraging critical thinking skills. Short boxed readings called “Math Minutes” explain the math behind the biology. Microarray images and all art and figures from the text are available on the free image presentation CD-ROM. The Discovering Genomics, Proteomics, and Bioinformatics website helps students learn about cutting-edge research and visualize complex processes. This integrated learning package sets the standard for material in the exciting new field of genomics.

Discovering Genomics, Proteomics, and Bioinformatics is the first in a series of books to be co-published by Cold Spring Harbor Laboratory Press and Benjamin Cummings.

Table of Contents

I. GENOMIC SEQUENCES.

1. Genome Sequence Acquisition and Analysis.
2. Genome Sequences to Answer Interesting Questions.
3. Genomic Variations.

II. GENOMIC EXPRESSION.

4. Basic Research with DNA Microarrays.
5. Applied Research with Microarrays.
6. Proteomics.

III. WHOLE GENOME PERSPECTIVE.

7. Genomic Circuitry in Single Genes.
8. Integrated Genomic Circuits.
9. Modeling Whole-genome Circuits.

IV. TRANSITION FROM GENETICS TO GENOMICS: MEDICAL CASE STUDIES.

10. What's Wrong with My Child?
11. Why Can't I Just Take a Pill to Lose Weight?
12. Why Can't We Cure More Diseases?