Oncology: Genomics, Precision Medicine and Therapeutic Targets

Tuli, Hardeep Singh, Yerer Aycan, Mükerrem Betül

  • 出版商: Springer
  • 出版日期: 2024-07-02
  • 售價: $3,970
  • 貴賓價: 9.5$3,772
  • 語言: 英文
  • 頁數: 274
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 9819915317
  • ISBN-13: 9789819915316
  • 海外代購書籍(需單獨結帳)

商品描述

This book describes translational cancer therapeutics and the way forward from clinical and molecular diagnosis to treatment. In addition, genomics alterations, microRNAs, and long non-coding RNAs translate precision medicine for the individualistic therapy of cancer patients. It describes the involvement of various pharmacogenetic factors in pharmacodynamic/pharmacokinetic (PD/PK) modulations of medicines. Indeed, the role of bioinformatics and biostatistics, considering the extensive data analysis serving precision medicine approaches, has also been entertained in the present book. Therefore, intended book demonstrates the successful medical evidence for the use of precision medicine in the treatment of cancer and its future clinical perspectives. It fills the gaps in cancer biology and precision medicine with its up-to-date content and well-designed chapters. It will serve as a valuable resource for science, medical students, and interdisciplinary researchers. It is a very welcome addition for the scientific community, research centers, and university-industry research collaborators to find out a complete capsular package about cancer drug targets, precision, and personalized medicine (including an introduction to cancer cell signaling, genomic alterations, miRNA targeting, pharmacogenetics, biomarkers, and metabolomics in precision medicine, etc.) at a single platform.

商品描述(中文翻譯)

本書描述了轉譯癌症治療的過程,以及從臨床和分子診斷到治療的未來方向。此外,基因組變化、微小RNA和長非編碼RNA將精準醫療轉化為癌症患者的個體化治療。書中還描述了各種藥物基因組學因素在藥效學/藥物動力學(PD/PK)調節中的參與。事實上,考慮到為精準醫療方法服務的廣泛數據分析,生物信息學和生物統計學的角色在本書中也得到了探討。因此,本書展示了精準醫療在癌症治療中的成功醫學證據及其未來臨床前景。它以最新的內容和精心設計的章節填補了癌症生物學和精準醫療之間的空白。對於科學、醫學學生和跨學科研究人員來說,它將成為一個寶貴的資源。這對於科學社群、研究中心以及大學與產業的研究合作夥伴來說,都是一個非常受歡迎的補充,能夠在單一平台上找到有關癌症藥物靶點、精準醫療和個性化醫療(包括癌細胞信號傳導、基因組變化、miRNA靶向、藥物基因組學、生物標記和代謝組學等)的完整資訊包。

作者簡介

Dr. Hardeep Singh Tuli is an assistant professor at the Department of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana, India. His research interests focus on the isolation, characterization, and biochemical evaluation of natural metabolites as anticancer agents. He has served as a reviewer for several international journals and as a guest editor for Frontiers in Pharmacology. He has more than ten years of teaching and research experience in pharmacology, mammalian physiology, and natural products. He has published more than 100 papers in peer-reviewed international journals and authored several book chapters. He edited six international books in the area of cancer biology and chemoprevention. Dr. Tuli is an editorial board member of various national and international scientific research journals. In addition, he is in the top 2% of highly cited research in pharmacology.

Prof. Dr. M. Betül Yerer Aycan is working as the Deanof the Faculty of Pharmacy at Erciyes University and as the Director of the Erciyes University Pharmaceutical Application and Research Center accrediting the Pharmaceutical Application and Research Center in eight different categories. Prof. Dr. M. Betül Aycan has more than 100 publications, more than 70 of which are SCI, on the use of natural compounds in neuropsychopharmacology and cancer research, many international book/book chapters, and national and international awards.


作者簡介(中文翻譯)

Dr. Hardeep Singh Tuli 是印度馬哈希里·馬爾坎德什瓦爾(被認定為大學)生物技術系的助理教授。他的研究興趣集中在天然代謝物的分離、特徵化及生化評估,作為抗癌劑。他曾擔任多本國際期刊的審稿人,並擔任《Frontiers in Pharmacology》的客座編輯。他在藥理學、哺乳動物生理學和天然產品方面擁有超過十年的教學和研究經驗。他在同行評審的國際期刊上發表了超過100篇論文,並撰寫了幾個書籍章節。他編輯了六本有關癌症生物學和化學預防的國際書籍。Dr. Tuli 是多本國內外科學研究期刊的編輯委員會成員。此外,他在藥理學領域的高被引研究中位居前2%。

Prof. Dr. M. Betül Yerer Aycan 擔任埃爾基耶斯大學藥學院院長及埃爾基耶斯大學藥物應用與研究中心主任,負責在八個不同類別中認證藥物應用與研究中心。Prof. Dr. M. Betül Aycan 擁有超過100篇出版物,其中超過70篇為SCI論文,專注於天然化合物在神經精神藥理學和癌症研究中的應用,並擁有多本國際書籍/書籍章節以及國內外獎項。