商品描述
This open-access book presents recent advances in our understanding of the nano-structure of synaptic junctions in terms of their organization, mechanisms of assembly, and role in neuronal signaling as well as plasticity. Traditionally, a single synapse was assumed to have a homogeneous organization of molecular components both at the active zone and postsynaptically. Recent advances in imaging tools and the further elucidation of the physiological significance of distinct forms of release have challenged this notion. This is a timely book that will richly contribute to the ongoing efforts to develop this novel perspective into the study of the nervous system.
商品描述(中文翻譯)
這本開放存取的書籍介紹了我們對突觸接合處納米結構的最新理解，包括其組織、組裝機制以及在神經信號傳遞和可塑性中的角色。傳統上，單一突觸被認為在活躍區和突觸後區的分子組件具有均質的組織。最近在成像工具的進步以及對不同釋放形式生理意義的進一步闡明，挑戰了這一觀念。這是一本及時的書籍，將對於將這一新穎視角發展成為神經系統研究的持續努力做出豐富的貢獻。
作者簡介
Dr. Kavalali was born and raised in Istanbul, Turkey. He studied Electrical Engineering at Boğaziçi University in Istanbul. In 1995, he received his Ph.D. degree in Biomedical Engineering from Rutgers University. In 1999, he completed his postdoctoral studies at Stanford University in the Department of Molecular and Cellular Physiology. He then joined the faculty at the Center for Basic Neuroscience at UT Southwestern Medical Center at Dallas where he rose to the rank of Professor in the Departments of Neuroscience and Physiology. He also held the Rosewood Corporation Chair, in addition to serving as the Chair of the Neuroscience Graduate Program between 2008 and 2016. In 2018, Dr. Kavalali joined the Department of Pharmacology at Vanderbilt University as a Professor and the William Stokes Chair in Experimental Therapeutics. He currently serves as the Chair of the Department.
作者簡介(中文翻譯)
卡瓦拉利博士出生並成長於土耳其伊斯坦堡。他在伊斯坦堡的博斯普魯斯大學（Boğaziçi University）學習電機工程。1995年，他在羅格斯大學（Rutgers University）獲得生物醫學工程的博士學位。1999年，他在斯坦福大學（Stanford University）分子與細胞生理學系完成了博士後研究。隨後，他加入德州大學西南醫學中心（UT Southwestern Medical Center）基礎神經科學中心的教職，並在神經科學與生理學系晉升為教授。他還擔任了玫瑰木公司（Rosewood Corporation）講座教授，並在2008年至2016年間擔任神經科學研究生課程的主任。2018年，卡瓦拉利博士加入范德堡大學（Vanderbilt University）藥理學系，擔任教授及威廉·斯托克斯（William Stokes）實驗治療學講座教授。目前，他擔任該系主任。
