Metabolic Neuropsychiatry
暫譯: 代謝神經精神病學

Öngür, Dost, Ford, Judith M.

Metabolic Neuropsychiatry
  • 出版商: Springer
  • 出版日期: 2025-10-04
  • 售價: $2,540
  • 貴賓價: 9.5 折 $2,413
  • 語言: 英文
  • 頁數: 319
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 3032056292
  • ISBN-13: 9783032056290

    • 海外代購書籍(需單獨結帳)

商品描述

This open access book provides an interdisciplinary perspective on energy metabolism in the brain and body in neuropsychiatric disorders and suggests future research directions.

Multiple lines of evidence indicate that energy metabolism is aberrant in the body and brain in individuals with major neuropsychiatric disorders such as schizophrenia, mood disorders, and neurodegenerative disorders. Emerging therapeutic interventions aim to improve outcomes in many of these common and severe disorders. To foster interdisciplinary dialogue and to promote informed applications in research, medicine, and public health, the Ernst Strüngmann Forum convened scholars from diverse fields to examine the role of energy metabolism in brain function, the bidirectional association between metabolism in the brain and body, and the future therapeutic potential of treatment interventions that improve metabolism in people with psychiatric disorders.

Synthesizing the interdisciplinary perspectives that emerged from these discussions, the book is organized in four sections:

  • Role of Metabolism in Brain Function
  • Metabolic Abnormalities in Neuropsychiatric Disorders
  • Systemic Metabolic Aspects of Neuropsychiatric Disorders
  • Metabolism-Based Therapies

This volume offers insights to researchers and clinicians working in basic, translational, and clinical research in neurology and psychiatry pertinent to mitochondrial function, energy metabolism, human physiology, and treatment development.

商品描述(中文翻譯)

這本開放存取的書籍提供了關於神經精神疾病中大腦和身體能量代謝的跨學科視角，並建議未來的研究方向。

多項證據顯示，患有主要神經精神疾病（如精神分裂症、情緒障礙和神經退行性疾病）的人在身體和大腦中的能量代謝異常。新興的治療干預旨在改善這些常見且嚴重疾病的結果。為了促進跨學科的對話並推動在研究、醫學和公共衛生中的知情應用，Ernst Strüngmann Forum召集了來自不同領域的學者，檢視能量代謝在大腦功能中的角色、大腦與身體之間的雙向關聯，以及改善精神疾病患者代謝的治療干預的未來治療潛力。

綜合這些討論中出現的跨學科觀點，本書分為四個部分：
- 代謝在大腦功能中的角色
- 神經精神疾病中的代謝異常
- 神經精神疾病的系統性代謝方面
- 基於代謝的療法

本卷為從事神經學和精神病學基礎、轉化及臨床研究的研究人員和臨床醫生提供了有關線粒體功能、能量代謝、人類生理學和治療開發的見解。

作者簡介

Dost Öngür: A native of Istanbul, Turkey, Dr. Öngür obtained his M.D./Ph.D. degree from Washington University in St. Louis and psychiatric residency training at the MGH/McLean Adult Psychiatry program. He is currently the William P. and Henry B. Test Professor of Psychiatry at Harvard Medical School and Chief of the Psychotic Disorders Division at McLean Hospital.
Dr. Öngür's research uses neuroimaging approaches to probe brain abnormalities in psychotic disorders as well as clinical studies to understand the trajectories of illness in early phases of these disorders. His work has been continuously funded by the NIH and other sources for over two decades, including a current P50 Center grant focused on early psychosis research. His work using magnetic resonance spectroscopy has documented extensive bioenergetic abnormalities in the brain in schizophrenia and bipolar disorder. He is also an active clinician and an administrator responsible for all clinical services serving patients with psychotic disorders at McLean.
Dr. Öngür has won awards from McLean Hospital and Harvard Medical School for his teaching and mentoring, and the Kempf and Gralnick Awards from the APA. He has served on Council for professional organizations such as the ACNP, SOBP and SIRS, and serves on the Scientific Council for NARSAD/BBRF. Most recently, he was elected to serve as President for SOBP during 2026-2027. Finally, since 2018 he is the Editor in Chief of JAMA Psychiatry, a premier journal in the field.

Judith M. Ford: Dr. Ford obtained her Ph.D. in Neuroscience from Stanford University School of Medicine in Stanford, California. She served on the faculty of Psychiatry and Behavioral Sciences at Stanford until 2004, when she left to join the Psychiatry faculty at Yale University School of Medicine. In 2007, she returned to California to join the Psychiatry faculty at the University of California San Francisco.
Dr. Ford's research uses neuroimaging, including EEG, to understand the biological basis of psychotic disorders. Her work has been continuously funded by the NIH and, more recently, by the Veterans Administration. Her most recent NIH grant funds a mechanistic clinical trial asking if neural network instability in schizophrenia and psychotic bipolar disorder can be improved with a very low carbohydrate ketogenic diet.
Dr. Ford won the Middleton Award from the Veterans Administration for her basic neuroscience work elucidating the pathophysiology of serious mental illnesses and the lifetime achievement award from the Society for Psychophysiological Research. She has served on councils for professional organizations such as the ACNP and SOBP, and currently serves on SOBP Council as Past President and on the Board of Directors for the International Organization of Psychophysiology. Since 2007, she has served on the Scientific Council for NARSAD/BBRF, she co-chairs the Young Investigator grant program, and recently became President of the BBRF Scientific Council. She is on the editorial boards of Schizophrenia Bulletin, Biological Psychiatry: Cognitive Neuroscience, and Neuroimage Clinical.

作者簡介(中文翻譯)

Dost Öngür：土耳其伊斯坦堡人，Öngür博士在聖路易斯華盛頓大學獲得醫學博士/哲學博士學位，並在麻省總醫院/麥克林成人精神醫學計畫接受精神科住院醫師訓練。他目前是哈佛醫學院威廉·P·和亨利·B·特斯特精神醫學教授，以及麥克林醫院精神病障礙科的主任。
Öngür博士的研究利用神經影像學方法探討精神病障礙中的大腦異常，並進行臨床研究以了解這些疾病早期階段的病程。他的研究已獲得國家衛生研究院（NIH）及其他來源的持續資助超過二十年，包括目前專注於早期精神病研究的P50中心撥款。他使用磁共振光譜技術的研究已記錄到精神分裂症和雙相情感障礙患者大腦中廣泛的生物能量異常。他也是一名活躍的臨床醫生及管理者，負責麥克林醫院所有為精神病患者提供的臨床服務。
Öngür博士因其教學和指導工作獲得了麥克林醫院和哈佛醫學院的獎項，以及美國精神醫學會（APA）的Kempf和Gralnick獎。他曾在ACNP、SOBP和SIRS等專業組織的理事會任職，並在NARSAD/BBRF的科學委員會中服務。最近，他被選為2026-2027年SOBP的會長。最後，自2018年以來，他擔任《JAMA Psychiatry》主編，這是該領域的頂尖期刊。

Judith M. Ford：Ford博士在加州史丹佛大學醫學院獲得神經科學博士學位。她曾在史丹佛的精神醫學與行為科學系任教，直到2004年離開，加入耶魯大學醫學院的精神醫學系。2007年，她返回加州，加入加州大學舊金山分校的精神醫學系。
Ford博士的研究利用神經影像學，包括腦電圖（EEG），以了解精神病障礙的生物學基礎。她的研究持續獲得NIH的資助，最近也獲得退伍軍人事務部的資助。她最近的NIH撥款資助一項機制臨床試驗，探討精神分裂症和精神病雙相情感障礙的神經網絡不穩定性是否可以通過非常低碳水化合物的生酮飲食來改善。
Ford博士因其闡明嚴重精神疾病病理生理學的基礎神經科學工作而獲得退伍軍人事務部的米德爾頓獎，以及心理生理研究學會的終身成就獎。她曾在ACNP和SOBP等專業組織的理事會任職，目前擔任SOBP理事會的前會長，以及國際心理生理學組織的董事會成員。自2007年以來，她一直在NARSAD/BBRF的科學委員會任職，並共同主持年輕研究者撥款計畫，最近成為BBRF科學委員會的會長。她還是《精神分裂症公報》、《生物精神醫學：認知神經科學》和《臨床神經影像學》的編輯委員會成員。

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