Cancer Neuroscience
Amit, Moran, Scheff, Nicole N.
- 出版商: Springer
- 出版日期: 2024-07-27
- 售價: $7,700
- 貴賓價: 9.5 折 $7,315
- 語言: 英文
- 頁數: 202
- 裝訂: Quality Paper - also called trade paper
- ISBN: 3031338405
- ISBN-13: 9783031338403
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相關主題
商品描述
This volume is the first on the market to address and discuss the emerging field of cancer neuroscience. Edited by pioneers in the field with contributions from top researchers, the volume serves as a comprehensive overview of the role of nerves in tumorigenesis and cancer progression. Chapters will address how the innervation of tumors can serve as both prognostic and predictive biomarkers as well as actionable therapeutic targets. Authors will describe current research efforts, and future directions for study and translation to the clinic. It is becoming increasingly apparent that certain treatments will need to consider interactions between the nervous system and cancer, and the novel concepts presented in the book address related accumulating evidence regarding therapeutic strategies.
This unique volume will be useful for cancer researchers, neuroscientists, cancer biologists, oncologists, and others looking to gain a greater understanding of this emerging field.商品描述(中文翻譯)
本書是市場上首部探討和討論癌症神經科學新興領域的著作。由該領域的先驅編輯，並由頂尖研究者貢獻，該書提供了神經在腫瘤生成和癌症進展中的角色的全面概述。各章將探討腫瘤的神經支配如何作為預後和預測生物標記，以及可行的治療目標。作者將描述當前的研究努力以及未來的研究方向和臨床轉化。越來越明顯的是，某些治療需要考慮神經系統與癌症之間的相互作用，而本書中提出的新概念針對與治療策略相關的累積證據進行了探討。
這本獨特的著作將對癌症研究者、神經科學家、癌症生物學家、腫瘤科醫生以及其他希望深入了解這一新興領域的人士有所幫助。
作者簡介
Dr. Amit is dedicated to key areas of cancer research that will develop therapeutic approaches to improve patients' survival, treatment responses, and quality of life. During his residency training, Dr. Amit became interested in the biology of cancer. After completing his residency, he undertook further training in Head and Neck Surgical Oncology at The University of Texas MD Anderson Cancer Center, where he completed a clinical fellowship as a head and neck surgical oncologist and a postdoctoral fellowship with a focus on the neurobiology of cancer.
Dr. Amit has an active research laboratory focusing on cancer-related neurogenesis and axonogenesis and on the role of neuro-immunology in cancer. One exciting finding of Dr. Amit's lab involved describing a mechanism by which head and neck tumors can reprogram adrenergic signaling in neurons and the effect of targeting the peripheral nervous system on cancer initiation and progression. This will serve as a basisfor combining treatments targeting the nervous system with other therapies, such as immunotherapy, in the treatment of head and neck cancers. Dr. Amit is continuing his work by building a team to study how the neural microenvironment affects responses to chemotherapy and immunotherapy in patients with non-melanoma skin cancer and other cancers, and to develop novel strategies to combat resistance to these therapies.
Dr. Scheff is Assistant Professor and Principal Investigator in the Center for Neuroscience at the Hillman Cancer Center Research Pavillion at the University of Pittsburgh Medical Center. Her research is focused on the neurobiology of head and neck cancer and orofacial pain.
作者簡介(中文翻譯)
Dr. Amit 專注於癌症研究的關鍵領域，旨在開發治療方法以改善患者的生存率、治療反應和生活品質。在他的住院醫師訓練期間，Dr. Amit 對癌症生物學產生了興趣。完成住院醫師訓練後，他在德克薩斯大學MD安德森癌症中心進行了頭頸部外科腫瘤學的進一步訓練，並完成了作為頭頸部外科腫瘤醫生的臨床研究員和專注於癌症神經生物學的博士後研究。
Dr. Amit 擁有一個活躍的研究實驗室，專注於與癌症相關的神經生成和軸突生成，以及神經免疫學在癌症中的角色。Dr. Amit 實驗室的一個令人興奮的發現是描述了一種機制，頭頸部腫瘤如何重新編程神經元中的腎上腺素信號傳遞，以及針對周邊神經系統對癌症發生和進展的影響。這將作為將針對神經系統的治療與其他療法（如免疫療法）結合的基礎，以治療頭頸部癌症。Dr. Amit 正在繼續他的工作，組建團隊研究神經微環境如何影響非黑色素瘤皮膚癌和其他癌症患者對化療和免疫療法的反應，並開發新策略以對抗這些療法的抗藥性。
Dr. Scheff 是匹茲堡醫療中心希爾曼癌症中心神經科學中心的助理教授和主要研究員。她的研究專注於頭頸部癌症和口面部疼痛的神經生物學。
