Bioinformatic and Statistical Analysis of Microbiome Data: From Raw Sequences to Advanced Modeling with Qiime 2 and R
Xia, Yinglin, Sun, Jun
- 出版商: Springer
- 出版日期: 2024-05-16
- 售價: $7,700
- 貴賓價: 9.5 折 $7,315
- 語言: 英文
- 頁數: 703
- 裝訂: Quality Paper - also called trade paper
- ISBN: 3031213939
- ISBN-13: 9783031213939
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商品描述
This unique book addresses the bioinformatic and statistical modelling and also the analysis of microbiome data using cutting-edge QIIME 2 and R software. It covers core analysis topics in both bioinformatics and statistics, which provides a complete workflow for microbiome data analysis: from raw sequencing reads to community analysis and statistical hypothesis testing. It includes real-world data from the authors' research and from the public domain, and discusses the implementation of QIIME 2 and R for data analysis step-by-step. The data as well as QIIME 2 and R computer programs are publicly available, allowing readers to replicate the model development and data analysis presented in each chapter so that these new methods can be readily applied in their own research.
Bioinformatic and Statistical Analysis of Microbiome Data is an ideal book for advanced graduate students and researchers in the clinical, biomedical, agricultural, and environmental fields, as well as those studying bioinformatics, statistics, and big data analysis.
商品描述(中文翻譯)
這本獨特的書籍探討了使用先進的QIIME 2和R軟體進行生物信息學和統計建模以及微生物組數據分析。它涵蓋了生物信息學和統計學的核心分析主題，提供了一個完整的微生物組數據分析工作流程：從原始序列讀取到群落分析和統計假設檢驗。書中包含了作者的研究和公共領域的真實數據，並逐步討論了使用QIIME 2和R進行數據分析的實施過程。這些數據以及QIIME 2和R的電腦程式都是公開可用的，讀者可以複製每章中所呈現的模型開發和數據分析，以便這些新方法可以輕鬆應用於他們自己的研究中。
《生物信息學和統計分析微生物組數據》是一本理想的書籍，適合臨床、生物醫學、農業和環境領域的高級研究生和研究人員，以及研究生物信息學、統計學和大數據分析的人士。
作者簡介
Dr. Yinglin Xia is a Research Professor in the Department of Medicine at the University of Illinois Chicago (UIC). He was a Research Assistant Professor in the Department of Biostatistics and Computational Biology at the University of Rochester (Rochester, NY) and Clinical Statistician in AbbVie (North Chicago, IL) before joining UIC as a Research Associate Professor in 2015. Dr. Xia has published more than 140 statistical methodology and research papers in peer-reviewed journals. He serves on the editorial board for several scientific journals including as an Associate Editor of Gut Microbes and has served as a reviewer for over 100 scientific journals. He is the lead authors of Statistical Analysis of Microbiome Data with R (Springer Nature, 2018), which was the first statistics book in microbiome study, Statistical Data Analysis of Microbiomes and Metabolomics(American Chemical Society, 2022) and An Integrated Analysis of Microbiomes and Metabolomics (American Chemical Society, 2022).
Dr. Jun Sun is a tenured Professor of Medicine at the University of Illinois Chicago. She is an elected fellow of the American Gastroenterological Association (AGA) and American Physiological Society (APS). She chairs the AGA Microbiome and Microbial Therapy section.
She is an internationally recognized expert on microbiome and human diseases, such as vitamin D receptor in inflammation, dysbiosis and intestinal dysfunction in amyotrophic lateral sclerosis (ALS). Her lab is the first to discover chronic effects and molecular mechanisms of Salmonella infection and development of colon cancer. Dr. Sun has published over 210 scientific articles in peer-reviewed journals and 8 books on microbiome. She is on the editorial boards of more than 10 peer-reviewed international scientific journals, including a Deputy Editor for American Journal of Physiology-GIL, an AssociateEditor for Gut Microbes. She serves on the study sections for the national and international research foundations.
作者簡介(中文翻譯)
Dr. Yinglin Xia是伊利諾伊大學芝加哥分校（UIC）醫學系的研究教授。在2015年加入UIC之前，他曾在羅切斯特大學（紐約羅切斯特）生物統計與計算生物學系擔任研究助理教授，並在AbbVie（伊利諾伊州北芝加哥）擔任臨床統計學家。Xia博士在同行評審期刊上發表了超過140篇統計方法論和研究論文。他擔任多個科學期刊的編輯委員會成員，包括《Gut Microbes》的副編輯，並擔任過100多個科學期刊的審稿人。他是《Statistical Analysis of Microbiome Data with R》（Springer Nature，2018）的主要作者，該書是微生物統計學研究領域的第一本統計學書籍，《Statistical Data Analysis of Microbiomes and Metabolomics》（美國化學學會，2022）和《An Integrated Analysis of Microbiomes and Metabolomics》（美國化學學會，2022）的主要作者。
Dr. Jun Sun是伊利諾伊大學芝加哥分校的醫學教授。她是美國胃腸病學會（AGA）和美國生理學會（APS）的當選會士。她擔任AGA微生物組和微生物治療部門的主席。
她是國際公認的微生物組和人類疾病專家，研究領域包括炎症中的維生素D受體、肌萎縮性脊髓側索硬化症（ALS）中的菌群失調和腸道功能障礙等。她的實驗室是第一個發現沙門氏菌感染和結腸癌發展的慢性影響和分子機制的。Sun博士在同行評審期刊上發表了超過210篇科學文章和8本關於微生物組的書籍。她是10多個同行評審的國際科學期刊的編輯委員會成員，包括《American Journal of Physiology-GIL》的副編輯和《Gut Microbes》的副編輯。她還擔任國家和國際研究基金會的研究部門的成員。
