Modeling and Simulating Cardiac Electrical Activity
暫譯: 心臟電活動的建模與模擬

Krogh-Madsen, Trine, Christini, David J.

Modeling and Simulating Cardiac Electrical Activity
  • 出版商: IOP Publishing Ltd
  • 出版日期: 2020-12-03
  • 售價: $6,350
  • 貴賓價: 9.5 折 $6,033
  • 語言: 英文
  • 頁數: 236
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 0750320621
  • ISBN-13: 9780750320627

    • 海外代購書籍(需單獨結帳)

相關主題

商品描述

This book provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart, from molecular details of ionic channel dynamics to clinically derived patient-specific models. It discusses how cellular ionic models are formulated, introduces commonly used models and explains why there are so many different models available. The chapters cover modeling of the intracellular calcium handling that underlies cellular contraction as well as modeling molecular-level details of cardiac ion channels, and specialized topics such as cardiomyocyte energetics and signalling pathways. It is an excellent resource for experienced and specialized researchers in the field, but also biological scientists with a limited background in mathematical modelling and computational methods.

 

Key Features

  • Thorough introduction to the topic of mathematical modeling of electrical activity in the heart
  • Focuses on use of experimental data in mathematical modeling, and on explanations rather than equations
  • In addition to being experts in the field, the contributing authors are expert science communicators

商品描述(中文翻譯)

這本書提供了對心臟電活動數學建模主題的全面介紹，涵蓋了從離子通道動力學的分子細節到臨床衍生的病人特定模型。書中討論了細胞離子模型的形成，介紹了常用的模型，並解釋了為什麼會有如此多不同的模型可用。各章節涵蓋了細胞收縮所依賴的細胞內鈣處理的建模，以及心臟離子通道的分子層級細節建模，還有心肌細胞能量學和信號傳導路徑等專門主題。這是對於該領域的經驗豐富和專業研究人員的優秀資源，同時也適合對數學建模和計算方法背景有限的生物科學家。

主要特點

- 對心臟電活動數學建模主題的全面介紹
- 專注於在數學建模中使用實驗數據，並強調解釋而非方程式
- 除了是該領域的專家外，貢獻作者也是專業的科學傳播者

作者簡介

Trine Krogh-Madsen received a MSc in applied physics from the Technical University of Denmark and a PhD in physiology from McGill University. She is an Associate Research Professor in the Department of Medicine and at the Institute for Computational Biomedicine at Weill Cornell Medicine, New York.

David J Christini received a BS in electrical engineering from the Pennsylvania State University, and a MS and PhD in biomedical engineering from Boston University. After nearly 20 years as faculty member at Weill Cornell Medicine, he is currently a Professor of physiology and pharmacology at SUNY Downstate Health Sciences University, Brooklyn NY, where he also serves as Senior Vice President for Research.

作者簡介(中文翻譯)

Trine Krogh-Madsen 取得丹麥科技大學的應用物理碩士學位，以及麥吉爾大學的生理學博士學位。她是紐約威爾康奈爾醫學院醫學系及計算生物醫學研究所的副研究教授。

David J Christini 取得賓夕法尼亞州立大學的電機工程學士學位，以及波士頓大學的生物醫學工程碩士和博士學位。在威爾康奈爾醫學院擔任教職近20年後，他目前是紐約州立大學布魯克林分校健康科學大學的生理學與藥理學教授，同時擔任研究高級副校長。

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