Computational Systems Biology (Hardcover)

Table of Contents 

1. Introducing Computational Systems Biology. A Kriete and R Eils
I. Enabling Information and Integration Technologies for Systems Biology:
2. Databases for Systems Biology. J Eils, C Lawerenz, K Astrahantseff, M Ginkel, and R Eils
Natural Language Processing and Ontology-enhanced Biomedical Literature Mining for Systems Biology. X Hu
Integrated Imaging Informatics. B Parvin, G Fontenay, Q Yang, and MH Barcellos-Hoff
Simpathica: A Computational Systems Biology Tool within the Valis Bioinformatics Environment.
B Mishra, M Antoniotti, S Paxia and N Ugel
Standards, Platforms and Applications. HM Sauro
II. Foundations of Biochemical Network Analysis and Modeling
7. Introduction to Computational Models of Biochemical Reaction Networks.
FJ Bruggeman, BM Bakker, JJ Hornberg, and HV Westerhoff
8. Biological Foundations of Signal Transduction and the Systems Biology Perspective. U Klingmüller
9. Reconstruction of Metabolic Network from Genome Information and Its Structural and Functional Analysis.
H-W Ma and A-P Zeng
10. Integrated Regulatory and Metabolic Models. M.W. Covert
III. Computer Simulations of Dynamic Networks
11. A Discrete Approach to Network Modeling. R Laubenbacher and P Mendes
12. Gene Networks: Estimation, Modeling and Simulation. S Imoto, H Matsuno, and S Miyano
13. Computational models for circadian rhythms: Deterministic versus stochastic approaches.
J-C Leloup, D Gonze, and A Goldbeter
IV. Multi-Scale Representations of Cells and Emerging Phenotypes
14. Multistability and Multicellularity: Cell Fates as High-dimensional Attractors of Gene Regulatory Networks. S Huang
15. Spatio-Temporal Systems Biology. A Ghosh, D Miller, R Zou, B Sokhansanj,and A Kriete
16. Cytomics—from cell states to predictive medicine. G Valet, RF Murphy, JP Robinson, A Tárnok, A Kriete
17. The IUPS Physiome Project: Progress and Plans. P Hunter, K Burrowes, J Fernandez, P Nielsen,
N Smith, and M Tawhai
Subject Index